Time course of left ventricular pressure-volume relationship under various extents of aortic occlusion.

The author has reported that a variable, e(t)=p(t)/v(t), is approximately unchanged in the areflexive heart of the dog over a wide range of end-diastolic volume of the left ventricle, where p(t) is systolic left intraventricular pressure, v(t) is systolic left intraventricular volume, and t is time from the beginning of systole in each cardiac cycle. e(t) is studied further under various extents of an aortic occlusion, without the change in left intraventricular end-diastolic volume, monitored on left intraventricular end-diastolic pressure of the areflexive heart of the dog. For actual computation,